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Conclusion: ANA and SMA have moderate and low sensitivity for high-grade ICI hepatitis, though the prognostic implications of ANA- or SMA-positivity suggest that testing for these autoantibodies may be useful

The compound has since remained an active subject of preclinical research, particularly in the areas of lipid metabolism, adipose tissue signaling, and exploratory tissue repair models

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635 A double-blind, randomized, placebo-controlled trial of LX-9211 for pain relief and safety in DPN initially found that LX-9211 improved PDPN

The results revealed no significant differences in cerebral GSH or GABA levels between the ASD and TDC groups across all examined regions