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Tgf-Beta1-Mediated repression of Slc7a11 drives vulnerability to Gpx4 inhibition in hepatocellular carcinoma cells

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Figure 4: Glutathione conjugation with 1,2-dibromoethane causing formation of the highly reactive episulphonium ion [Figure source: Timbrell (2009) Biochemical Mechanisms of Toxicity.4 th Ed