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synthesized a pH-responsive COF material and encapsulated the photothermal agent heteropoly blue (HPB) in the COF by one-pot method to form HPB@COF nanoparticles in situ (Wang et al., 2022)

on the grounds that it could create serious damage to other cell populations by inducing massive free radical production instead [39]

e) New Checkpoint Inhibitors: Beyond PD-1 and CTLA-4 inhibitors, researchers are developing novel checkpoint inhibitors targeting other immune checkpoints