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In contrast to ghrelin, replacement of I178 4.60 or L181 4.63 by alanine demonstrates a more remarkable decreased GHRP-6s activity than F286 6.58 (Fig

Dehydroascorbate is reduced to ascorbate by dehydroascorbate reductase (DHAR) at the expense of GSH, yielding oxidized glutathione (GSSG)

A , B HK-2 cells were treated with MCTR1 (100 nM) and LPS (1 ug/ml) for 8 h

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First, the narrow therapeutic window poses challenges, as NETs exhibit pro-inflammatory effects in the early stage of injury ( 24 hours), making it difficult for systemic administration to achieve precise temporal control