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2.4.1 Glial changes in ageing Activation of microglial cells is one of the main features associated with CNS senescence, with changes in morphology, functionality, and molecular expression levels

Such short-lived and low-intensity expression may fall below the detection threshold of conventional immunohistochemical methods, particularly when compared to choroid plexus, where FR levels are extremely high

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Additionally, it safeguards the mitochondria, the energy-producing component of the cell, and is present in quantities comparable to glucose, potassium, and cholesterol within the cell

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