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Additionally, ROS-mediated activation of p53 represses SLC7A11 transcription impairing cystine uptake via system Xc - and further diminishing GPX4 activity [17, 18] Mitochondria significantly contribute to ferroptosis via oxidative metabolism

A 1218 (2011) 52735278

The Modern Med 4-Step Peptide Experience Built for patients who want answers, not guesswork, and a plan that evolves with them

Adv Nutr (2011) 2:12937

Toxicol In Vitro 17:675680 Gomez-Lechon MJ, Ponsoda X, OConnor E, Donato T, Castell JV, Jover R (2003b) Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS