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Disulfidptosis is triggered by the abnormal accumulation of intracellular disulfide bonds, particularly evident in tumor cells that overexpress the cystine transporter SLC7A11 and are subjected to glucose starvation ( Figure 1 )

Moreover, increased staining of the redox-associated markers 8-OHdG, GADD45 and GP-1 were also detected within isolated bulbar melanocytes, although this change was not clearly associated with donor age or canities extent

Bogard MJ, del Giorgio PA, Boutet L, Chaves MC, Prairie YT, Merante A, Derry AM (2014) Oxic water column methanogenesis as a major component of aquatic CH4 fluxes Nat

Upon oral ingestion, BPC-157 directly contacts the gastric and intestinal lining, promoting mucosal integrity, accelerating ulcer healing, and protecting against various digestive insults including NSAIDs and stress

In light of these findings, there is great interest in investigating the mechanisms of other bioactive peptides in auditory hair cells under normal and pathological conditions