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Supported by many many others in academia, industry and advocacy, it is a testament to the importance of basic and translational science in changing our standard of care. The FDA has approved sacituzumab govitecan for first-line triple-negative breast cancer (TNBC) in two settings: As monotherapy for patients not eligible for immunotherapy, And with pembrolizumab for PD-L1positive disease

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Anti Cancer Agents Med Chem 9:763777

The histidine-tagged recombinant GST was affinity-purified using Ni-NTA agarose resin as follows

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