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Bykov I, Jrvelinen H, Lindros K: L-carnitine alleviates alcohol-induced liver damage in rats: role of tumour necrosis factor-alpha

Indeed, cachexia represents a global tissue deregulation, beyond musle wasting (Wyart et al., 2020) and other tissues are affected before skeletal muscle, such as the immune system

Basic Clin Pharmacol Toxicol 105:3036 Tufekci O, Gunes D, Ozoul C, Kolatan E, Altun Z, Yilmaz O, Akta S, Erbayraktar Z, Kirkim G, Mutafolu K, Soylu A, Serbetiolu B, Gneri EA, Olgun N (2009) Evaluation of the effect of acetyl l-carnitine on experimental cisplatin nephrotoxicity

A study following dialysis patients found that carnitine supplements reduced red blood cell deformity and increased overall red blood cell count in 3 months [40]

Microbiota-dependent metabolite trimethylamine-N-Oxide is associated with disease severity and survival of patients with chronic heart failure