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[DOI] [PMC free article] [PubMed] [Google Scholar] 104.Nabekura T., Koizumi Y., Nakao M., Tomohiro M., Inomata M., Ito Y

Originally identified in a screen for compounds selectively lethal to RAS-mutant cancer cells, RSL3 triggers ferroptotic cell death by inactivating GPX4, leading to the accumulation of toxic amounts of reactive oxygen species (ROS) and subsequent oxidative membrane damage [1]

Yang, Z., Li, J., Chen, F., Xu, L., Jin, Y., Xu, S., et al

Genetic polymorphisms in drug-metabolizing enzymes further complicate toxicity profiles

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins