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To improve drug propertiessuch as stability and anticancer activityof diazeniumdiolate-based NO donors, a number of new molecules were synthesized and biologicaly evaluated 109,125,126

By recognizing that one is an accelerator and the other is a stabilizer, researchers can perfectly align their choice with their experimental endpoints and generate highly accurate data

Functional and pharmacological evaluation of novel GLA variants in Fabry disease identifies six (two de novo) causative mutations and two amenable variants to the chaperone DGJ

Preclinical and animal studies validate the clinical findings on AOD 9604 by demonstrating its clear impact on fat metabolism and 3-adrenergic receptor activity

doi: 10.3389/fimmu.2019.02972 80 WuSYFuTJiangYZShaoZM