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Vorinostat combined with DAC and cytarabine yielded 35% ORR in R/R AML with acceptable tolerability (Stein et al., 2021)

It is possible that the decline in therapeutic effect could have been due to the aggressiveness of the cone degeneration in the rd10 mice [34], or potential issues with storing the drug solution during experimentation

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Cells (3 10 5 ) were then plated on six-well plates and infected with the viral supernatant in the presence of 4 g ml 1 polybrene