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Description

In Fibromyalgia, reduced levels of adenosine are also implicated in pain modulation

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Mechanism: Structural support versus signaling modulation

The D-Nle-Trp-Ile-NH-(CH 2 )5- CONH 2 analog had intermediate inhibitory activity, and the D-Nle-Met-Ile-NH-(CH 2 )5- CONH 2 analog showed no ability to effect on Met activation