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In the ischemic penumbra, neurons predominantly undergo ferroptosis, while astrocytes in the ischemic core are more prone to pyroptosis

Furthermore, dual-targeting nanovaccines composed of heterocyclic lipids (A18) and polyesters (BR647) simultaneously incorporating oligomeric hyaluronic acid and DMG-PEG2000-mannose and encapsulating STAT3 siRNA and model antigens, can activate the STING pathway and promote the polarization of tumor-associated neutrophils from N2 to N1 (115)

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From signalling pathways to targeted therapies: unravelling glioblastoma's secrets and harnessing two decades of progress

KPV also has oral use cases for gut-focused protocols