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Similarly, a study focusing on CLOCK-related circadian regulators in nurses, found that hypermethylation in BMAL1 gene bodies was associated with working 3 consecutive NS per week, suggesting possible epigenetic silencing affecting CLOCK transcriptional activity

In the initial phase of the watermaze in which rodents search for the hidden platform, in each trial the rodent has only to bump into the platform once to locate it and escape

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