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Blood (1999) 93:165867

Further characterization of the HUVEC/NHDF approach shows that the pharmacological and physiological effects on endothelial cell biology are highly translatable to previous in vivo characterizations, exemplified by DLL4/Notch inhibition resulting in increased branch point formation late in the angiogenic process [3941]

The peptide appears to function as a broad regulatory molecule affecting multiple physiological systems

In young men, FOXO4 was predominantly found in the cytoplasm of Leydig cells, whereas in elderly men, it was primarily localized in the nucleus