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PSC mainly affects the large bile ducts with a characteristic pattern of multifocal strictures and dilations, while PBC targets small intrahepatic bile ducts

Oral administration has the benefit of high patient compliance and has demonstrated the potential to target brain iron pathology, especially with BBB-permeant agents like DFP

This is common in sport or work activities that require frequent and repeated use of the arm, especially when the arm motions are performed overhead

[32] [33] [34] Inhibition [edit] In unstimulated cells, the NF-B dimers are sequestered in the cytoplasm by a family of inhibitors, called IBs (Inhibitor of B), which are proteins that contain multiple copies of a sequence called ankyrin repeats