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doi: 10.1210/jc.2011-1802

The anti-inflammatory effect of silybin primarily manifests in the inhibition of excessive activation of immune cells and the release of inflammatory factors

We therefore hypothesized that PBAT-MPs induce neurotoxicity indirectly by disrupting gut microbial homeostasis and activating a gutbrain inflammatory cascade

Altered metabolism may thus participate in the signal-directed programs that promote or inhibit inflammation

In the future, this therapy may be an effective option for adults who are struggling with obesity or excess weight, especially if previous attempts with diet and exercise alone have not led to lasting results