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Ferroptosis suppressor protein 1 (FSP1) (also known as AIFM2) localizes to cellular membranes in a myristoylation-dependent manner, where it reduces ubiquinone (CoQ10) to ubiquinol (CoQH) using NAD(P)H, thereby generating a potent radical-trapping antioxidant pool that suppresses lipid peroxidation outside mitochondria

Its primary roles include: Red Blood Cell Formation : B12 is essential for the production of healthy red blood cells, preventing anaemia

F.BaldassarreH

Mar 26 2020;17(7)doi:10.3390/ijerph17072227

In vitro interaction assays uncover intrinsic differences in binding selectivity of Histone fold domains, with HFD-Taf12L displaying strong preference for Ada1, while HFD-Taf12 exhibits more promiscuous binding