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doi: 10.1055/s-0035-1565083

Iron-induced -syn aggregation can contribute to dopaminergic neurodegeneration through additional mechanisms, potentially creating a feedback loop in which -syn further enhances iron accumulation, thus perpetuating a vicious cycle of neurotoxicity

Although vitamin B 12 deficiency is known to damage the myelin sheath covering cranial, spinal, and peripheral nerves, the biochemical processes leading to neurologic damage in vitamin B 12 deficiency are not yet fully understood (22)