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We first investigated the effect of CAF-derived CM on the TGF1/SMAD2/3 pathway in A431 and SCC13 cells

As healthcare professionals, it is our responsibility to stay informed, apply emerging evidence thoughtfully, and prioritize patient-centered outcomes

Mitochondria regulation in ferroptosis

However, silencing the expression of endogenous ATF4 using a small interfering RNA (siATF4) significantly increased the cell proliferation inhibition rate (Figure 6A)