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Vernadsky Crimean Federal Univ., Simferopol, Russia, 2 Naarayani Multispeciality Hospital, Erode, India Objective: There is a huge number of risk factors of osteoporosis development, among which there are modifiable: taking glucocorticoids or low weight and unmodified factors: gender, chronic diseases, age over 60 y

Supported by MHCZ 00064203 Conflict of interest: All authors: nothing to disclose P776 Tandem high dose chemotherapy and autologous hematopoietic cell transplantation in newly diagnosed pediatric patients with malignant brain tumors - a Portuguese transplantation center experience Joana Desterro 1 , Filipe Gonalves 1 , Sofia Nunes 2 , Duarte Salgado 2 , Filipa Moita 1 , Maria Joo Gutierrez 1 , Gilda Teixeira 1 , Nuno Miranda 1 , Isabelina Ferreira 1 , Manuel Abecasis 1 1 1 2 2 1 1 1 1 1 1 1 Instituto Portugus de Oncologia de Lisboa, Hematologia, Lisboa, Portugal