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Acute pain develops as a result of exposure to noxious stimuli (13)(14)

GLS1 converts glutamine into glutamate [46]

These mechanisms may differ for RBC of patients with hereditary anemias or polycytemia and those observed in RBC during storage

Similarly, RNA-modifying enzymes, particularly m6A methyltransferases, influence DAT endocytosis by regulating the synthesis and functionality of associated proteins (Jiang et al., 2021)

It is not known whether these effects have any clinical relevance in AML, e.g., for the chemosensitivity during antileukemic therapy and/or in the immunoregulation of pancytopenic AML patients receiving intensive chemotherapy or allogeneic stem cell transplantation (Section 5.1 and Section 7.1)