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Two older studies published in 1981 and 1986 described mixed results in the intestinal histologic response of 7 patients with celiac disease and dermatitis herpetiformis after a trial of elemental diet despite significant improvement in their skin lesions, although these studies were limited by having used Crosby-Kugler capsules to obtain the small bowel biopsies [28, 29]

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This approach avoids the digestive system, allowing nutrients to be delivered in a more direct and controlled way

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