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Safety Profile Toxicology studies using doses far exceeding human therapeutic ranges have not identified significant adverse effects

Dendrite length was determined using the National Institutes of Health's Image J 1.41o program (NIH, Bethesda, Md.) and the neurite tracing program Neuron J (Meijering, Jacob et al

An optimized vitrification protocol Based on stereomicroscopy assessment of tissue swelling and crystallization, as well as the degree of electrophysiological recovery, we optimized a vitrification procedure that minimizes damage from the following six variables ( 35, 39 ): 1

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found that trehalose treatment significantly inhibited Cd-stimulated nuclear translocation of Nrf2 and the subsequent elevated expression of Nrf2-downstream targets in rat liver 36