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Histopathological findings with muscle biopsies have been another source of controversy in defining clinical features of LS

Stimuli such as shear stress, vascular endothelial growth factor (VEGF), and insulin activate kinases including protein kinase B (Akt), AMP-activated protein kinase (AMPK), calcium/calmodulin-dependent protein kinase II (CaMKII), protein kinase A (PKA), and protein kinase G (PKG), which phosphorylate Ser1177 (Fulton et al., 1999

Burkholderia pseudomallei as an enteric pathogen: identification of virulence factors mediating gastrointestinal infection

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