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Given that the regulation of the intracellular cytoskeleton is dependent on the presence of ATP to stimulate the contraction of actin-myosin complexes, a reduction in ATP concentration caused by NSAIDs was found to impair TJs and reduce cellular polarity (Knig et al

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Isomalt is an equimolar mixture of two mutually diastereomeric disaccharides, each composed of two sugars: glucose and mannitol --D-glucopyranosido-16-mannitol- and also glucose and sorbitol --D-glucopyranosido-16-sorbitol-