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Due to this muscular rigidity, slowness of movement and slowness of initiation of movement occur

Nat Rev Endocrinol 5:374 Citrome L (2013) A review of the pharmacology, efficacy and tolerability of recently approved and upcoming oral antipsychotics: an evidence-based medicine approach

host disease in bone marrow recipients (7880)

Across recent studies, mechanical cues shape aging phenotypes in a rhythm- and dose-dependent manner: prolonged circadian-like compression and rapid cyclic uniaxial stretch reproducibly yield pro-aging features (greater wrinkles/roughness, elevated ROS and -gal, reduced TGF- receptor signaling, and suppressed collagen synthesis), whereas low-magnitude periodic tensile loading produces mixed, context-dependent effects on barrier-associated readouts and matrix organization 16,17,117,118

Clinical validation of rcsms: a rapid and sensitive crispr-cas12a test for the molecular detection of sars-cov-2 from saliva