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Cumhuriyet Dent J

Obiri et al

Targeting of the Glutathione, Thioredoxin, and Nrf2 Antioxidant Systems in Head and Neck Cancer

Right gel shows a lot of GST-fusion protein in the flow-through indicating that insufficient glutathione agarose resin was used for this purification

This study identifies that in PDA ME2 is near the SMAD4 locus and is lost concurrently with SMAD4 deletion, conferring a unique dependency for PDA on ME3 activity