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The immune system produces autoantibodies against nuclear components (DNA, histones, ribosomes), and immune complex deposition causes inflammation in kidneys, skin, joints, brain, and blood vessels

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Results were expressed as mU/mg the protein taking into account that 1 U is defined as the amount of the enzyme that catalyzes the conversion of one micromole of substrate per minute (mol/min) under the specified conditions of the assay method

Ignoring this could lead to a peptide losing activity faster (for instance, through degradation of sensitive bonds)

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