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Full Ingredients (extracted from numbuzin Official Website) Water, Niacinamide, Dipropylene Glycol, Glycerin, Propanediol, Butylene Glycol, Hydroxyethyl Urea, Diethoxyethyl Succinate, Hydroxyacetophenone, Caprylyl Glycol, Polyglyceryl-10 Laurate, Betaine, Panthenol, Ethylhexylalycerin, Gluconolactone, Sodium Polyacrylate, Ammonium Acryloydime thylaurate/VP Copolymer, Sodium Citrate, Citric Acid, Maltodextrin, 1,2-Hexanediol, Gardenia Florida Fruit Extract, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ascorbic Acid, Pantolactone, Tocopherol, Capryloyl, Salicylic Acid, Tranexamic Acid, Tremella Fuciformis (Mushroom) Extract, aprylic/Capric Triglyceride, Ascorbyl Glucoside, Ubiquinone, Hydrogenated Lecithin, Magnesium Chloride, Alcohol, Glutathione, Polysorbate 80, Calcium Gluconate, Pyridoxine HCl, BHT, Yeast Extract, Cyanocobalamin, Disodium EDTA Note: Some ingredients may vary depending on the countrys regulations

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Disruption of either the Nfkb1 or the Bcl3 gene inhibits skeletal muscle atrophy

While topical estrogen may reverse these changes, the effects of todays low-dose systemic hormone treatments are not well established, raising the need for more concentrated local administration of hormones or newer cosmeceutical agents such as selective estrogen receptor modulators (SERMs), including phytoestrogens that have become major active ingredients for skin care products, especially when addressing estrogen-deficient skin

3.3, n = 9 (IQR 2.8 to 4.3)