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To evaluate the role of AGO1/2 in the miR-214-induced expression of ferroptosis-driver genes, siRNAs targeting AGO1 and AGO2 were used to knock down their expressions

Occup Environ Med 55:393400

Detailed records of solution preparation, including which calculator was used and what inputs were entered

Within the intricate gut-kidney axis pathological framework, these therapeutic mechanisms collectively demonstrate rhubarbs multifaceted intervention across four critical junctures: orchestrating intestinal microbiome remodeling through selective bacterial modulation, reinforcing intestinal barrier integrity via colonic epithelial strengthening, optimizing microbial metabolite profiles through uremic toxin reduction and correction of aberrant fermentation processes, and ultimately providing direct renal cellular protection by attenuating both glomerulosclerotic progression and interstitial fibrogenesis

An Atlas of -Glucuronidases in the Human Intestinal Microbiome