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696 Abatacept for immune checkpoint inhibitor associated myocarditis (ATRIUM): a phase 3, investigator-initiated, randomized, double blind, placebo-controlled trial

The anabolic properties of GH suggest that the manipulation of the GH/IGF-1 axis may provide a possible therapeutic option for the treatment of many of the adverse changes which occur with ageing and in particular sarcopenia

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Cortisol is a potent catabolic hormone and immunomodulator that alters gene expression in virtually every tissue, so any GH secretagogue that co-elevates cortisol introduces a major confounding variable that requires additional control groups and complicates data interpretation in anabolic or metabolic studies