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[DOI] [PMC free article] [PubMed] [Google Scholar] 116.Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, et al

In the resting state, NMDAR channels are normally blocked by Mg 2+ , but when large amounts of glutamate accumulate, activated AMPAR causes partial depolarization of the postsynaptic membrane, sufficient to clear the Mg 2+ on the NMDAR

Additionally, glaucoma (increased eye pressure) has occurred in rare cases, so you should take your child in for an evaluation if any vision symptoms arise