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Among the studies reviewed, only eight met the criteria for analysis

doi: 10.1016/j.media.2019.05.010

The complexity of the IGF1 gene splicing, post-translational modification and bioactivity

Using an efficient method employing wheat germ agglutinin (WGA)-coupled magnetic beads for EV isolation, they identified three significantly elevated miRNAs miR-574-3p, miR-542-3p, and miR-200a-3p in MASLD patients compared to healthy controls

It also enables multi-dimensional intervention across the cancerimmunity cycle: enhancing antigen availability and danger signals, blocking inhibitory checkpoints, improving immune cell metabolism, and recruiting more effector cells