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doi: 10.3389/fimmu.2024.1437046 Received 23 May 2024 Accepted 12 July 2024 Published 02 August 2024 Volume 15 - 2024 Edited by Jinghua Peng, Shanghai University of Traditional Chinese Medicine, China Reviewed by Haiguang Wang, University of Minnesota Twin Cities, United States Li Wen, Yale University, United States Updates Copyright 2024 Abdelnabi, Hassan and Shoukry

Consequently, an increasing number of studies are focused on understanding the role of oxidation, particularly ROS, in the microenvironment and attempting to enhance anti-tumor immunotherapy by modulating ROS levels

2.2 Anoikis When a cell loses its normal connection to the stroma, it senses signaling abnormalities that trigger anoikis, leading to disruption of intracellular signaling and cell death

The resulting dry, reddish solid was stored at 20 C in light-protected vials until use

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