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FIGURE 5 3.6 Effect of DXN and TIR on antioxidant enzymes in the rat brain In the group treated with DXN, the relative expression levels of SOD and GPx were significantly reduced correlated to the control group, with p -values of less than 0.01 and 0.0001, respectively

Factors responsible for the liver's contribution to drug metabolism include that it is a large organ, that it is the first organ perfused by chemicals absorbed in the gut, and that there are very high concentrations of most drug-metabolizing enzyme systems relative to other organs

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Oct 2 2023;14(19):8951-8963

Their comparative analysis demonstrated the advantages of PRIT over RIT