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The increase in the activity or quantity of EnaC induces an increase in sodium reabsorption by epithelial cells, which plays a role in the development of Liddle syndrome

Tziortzi AC, Haber SN, Searle GE, Tsoumpas C, Long CJ, Shotbolt P, et al

doi: 10.1016/j.neulet.2005.10.022

The role of ROS as a pathological player has been reported in various other cancers including astrocytic and ependymal glial tumors 68 , colorectal cancer 69 , kidney tumor 70 and breast cancers 71