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A Therapeutic Use Exemption (TUE) would be required for legitimate medical use by an athlete, but it is very difficult to obtain for S2 substances

No commercial sponsor will fund that for a compound it cannot exclusively monetise

Pancreatitis and gallbladder disease are recognised class-effect risks associated with GLP-1-based therapies and should be considered even in the absence of specific retatrutide data

And many of the proteins in the body are polypeptides

This shortcoming frequently translates to incomplete tumor rejection, limited formation of immune memory, and insufficient systemic (abscopal) effects, thereby restricting the clinical utility of immunoadjuvant-only approaches