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Biomed Pharmacother 129:110485 Devos D, Krystkowiak P, Clement F, Dujardin K, Cottencin O, Waucquier N, Ajebbar K, Thielemans B, Kroumova M, Duhamel A, Destee A, Bordet R, Defebvre L (2007) Improvement of gait by chronic, high doses of methylphenidate in patients with advanced Parkinsons disease

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This feature could make it more accessible to individuals with specific health concernsthough medical guidance is always essential

Finally, although the correlations between the metabolome and microbiome were established using robust statistical analyses, there was limited statistical power and there are also limitations to the statistical approaches used herein (e.g., log transformation to resolve non-normal distribution and/or heteroscedasticity 103 )