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Hair and nail germ formation and elongation assay For the formation and elongation assay of hair and nail germs, primary skin dermal fibroblasts, skin epidermal keratinocytes, hair follicle dermal papilla cells, and nail fibroblasts (onychofibroblasts) were obtained from patients under ethical considerations

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This has been experimentally demonstrated by silencing the estrogen receptor in breast cancer (ER+) with consequent decrease of OCTN2 expression (Wang et al., 2012)