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Although GSH may function as a dynamic determinant of intracellular copper bioavailability rather than merely a passive buffering pool (Fig

However, TGF-1 has two sides: In addition to being an inducer driving fibrotic and anti-inflammatory responses, its inactivation may also mean exacerbating proinflammatory effects, suggesting that antifibrotic intervention that directly targets TGF- may trigger other unknown risks (145)

This study aims to further elucidate the relationship between lactate metabolism and PD and to investigate the potential regulatory effects of irisin on lactate metabolism

Reference Evans, OBrien, Ma, Hager, Riggins, Lambert and Riechers2017

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