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The enhanced cytotoxic effects of the p28-apoptin chimeric protein as a novel anti-cancer agent on breast cancer cell lines

Elevated levels of homocysteine and MMA and low levels of HoloTC confirm vitamin B12 deficiency (Figure 2).[7] Figure 2: Folate and methionine cycle Vitamin B12 deficiency leads to a decrease in S-adenosylmethionine (SAM), which decreases DNA methylation and myelination of neurons

276 In an uncontrolled clinical trial in 28 women with fibromyalgia, 1,000 mcg of vitamin B12 daily for 50 days reduced symptom severity and anxiety scores

MacDonald et al

At 2.5mg per week, a 10mg vial with 2ml of water provides exactly four doses