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The animals were then deeply anesthetized with 3% isoflurane and 50 mg/kg of ketamine followed by a laminectomy at lumbar level L2-L3, corresponding to the sacrocaudal spinal cord

There are also gene-specific minor criteria such as severe hypermetropia, characteristic craniofacial features, bilateral elbow contractures and radiographic findings, e.g

In some cases, deeper swelling, especially around the eyes, lips, hands, or feet, can occur

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