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In a study carried out by Johnson et al

FLS-RA in a later stage has elevated MCT4 levels (74)

However, the application of CeO x -based nanozyme to suppress ROS levels still faces the major challenge that Ce (III) would rapidly react with ROS to oxidize Ce (IV) in the pathological microenvironment, disrupting the original redox cycle to restrict its catalytic activity, so that it is essential to introduce an extra stabilizer to maintain the nanozyme function 18

HSL is the rate-limiting enzyme of diacylglycerol hydrolysis after initial triglyceride hydrolysis by adipose triglyceride lipase

Categorizing patients into decade-based groups allows for a more systematic comparison and analysis across different age ranges, which is a commonly used approach in similar studies 20