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10.1016/j.chembiol.2008.02.010 65 YoungS

The Interplay of Renin-Angiotensin System and Toll-Like Receptor 4 in the Inflammation of Diabetic Nephropathy

Overexpression of STAT3 leads to increased expression of SLC7A11 and plays a protective role in an intestinal ischemia/reperfusion-induced acute lung injury mouse model by reducing ferroptosis (95)

These mutations are associated with a better prognosis and improved response to therapy, making IDH status a key molecular marker in the WHO classification system for gliomas [75, 76]