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These findings underscore that GSH regulates ferroptosis not only through peroxide detoxification but also by coordinating iron trafficking and Fe-S cluster integrity, thereby coupling redox defense to core metabolic fitness

Reduction of the roGFP2 disulfide occurs via a monothiol mechanism and involves a ternary complex with GSH and PfGrx

Melatonin inhibits MUC5AC production via suppression of MAPK signaling in human airway epithelial cells

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Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses