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KEGG classification and enrichment analysis (Figure 5E) revealed that the metabolic reconfigurations predominantly affected Metabolic Pathways, Biosynthesis of Secondary Metabolites, and Microbial Metabolism in Diverse Environments, highlighting the extensive influence of GR on the bacteriums metabolic processes

doi: 10.1111/and.12452 70 PhanKCharltonOSmithSD

Before NMR analysis, the sample was reconstituted in 50 l of precooled 4 C methanol, centrifuged at 18,500 g for 10 minutes at 4 C and the resulting supernatant was transferred into a precooled 2 ml Eppendorf and then stored at -80 C [25]

10.1016/s0168-8278(00)80122-1 59

& Lundblad, R.L