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Is there a role for somatostatin and its analogs in Cushing's syndrome

If CPS1 is partially deficient, NCG may stimulate the remaining CPS1.40,41 Initially advocated to NAGS deficiency, its safety, its quick action, and its oral administration incite some authors to propose its use in neonates as soon as they are diagnosed with severe hyperammonemia even before diagnosis confirmation.27,28,40,42,43 The initial dosage is 200 mg/kg (100300 mg/kg) in bolus per nasogastric tube and then 200 mg/kg divided q3h to 6 h

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However, research still suggests that the basics as the most reliable route to sustainable weight loss is proper nutrition, regular physical activity , enough quality sleep, and solid stress management

Wang Z, Yang X, Chen D, Liu Y, Li Z, Duan S, et al