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Patients are often described at the threshold where psychiatry and neurology merge, with subacute behavioral change, agitation or psychosis-like symptoms, seizures, and an amnestic syndrome that appears abruptly too limbic to ignore ( The subset that drives the dilemma is defined by trajectory and immune signals What distinguishes the subset of published cases that has driven renewed interest is not the presence of this grammar, since infection alone can account for it, but the trajectory under therapy and the immunological signals captured in some reports

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